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EU Clinical Trial Registries

How SilverCancer searches EU CTR, EudraCT and ClinicalTrials.gov.

The European trials landscape

Finding recruiting trials for a specific patient in Europe requires searching three registries with different coverage, data structures and interfaces — which do not cross-reference each other. SilverCancer unifies them in one country-aware search.

EU Clinical Trials Register (EU CTR)

The EU Clinical Trials Register is the official registry under EU Clinical Trials Regulation No 536/2014, fully operational since 2022. It contains trial design, country-level recruitment status and eligibility criteria. All Phase II–IV trials involving investigational medicinal products in the EU must be registered here. Trials with EU-only sites may appear months before ClinicalTrials.gov.

EudraCT

EudraCT was the predecessor to EU CTR and remains the source for trials authorised before the regulatory transition. EudraCT numbers link to EU CTR entries for ongoing trials. SilverCancer searches both for complete coverage.

ClinicalTrials.gov

ClinicalTrials.gov is the world's largest trial registry. Most multinational oncology trials — including EORTC, SAKK, GECP, Brazilian and Canadian sites — register here. It carries the most structured eligibility criteria, making it valuable for eligibility-based filtering.

SilverCancer simultaneously queries all three registries. Results are deduplicated, enriched with country-level recruitment status and ranked by relevance to your query. The registry source is always shown alongside each result.

Eligibility matching

SilverCancer matches structured eligibility criteria against the clinical context in your query — tumour type, biomarker status, line of therapy, ECOG, country site availability. Eligibility matching is indicative. Always verify with the trial site before referring a patient.